高中锋
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高中锋,博士,学术教授,硕士生导师,山东省泰山学者青年专家,山东省优青。西南大学博士(导师:李念兵教授),华中科技大学博士后(导师:江雷院士、夏帆教授)。主要研究领域为DNA纳米技术、逻辑传感与界面检测。先后承担国家自然科学基金面上项目、青年科学基金,山东省优秀青年科学基金,中国博士后科学基金等多项科研项目,获济南市优秀科技工作者称号、获山东省自然科学二等奖(4/5),山东省循环经济科学技术奖三等奖(2/7)。在国际核心期刊Science Advances, Nature Protocols, Chem, National Science Review, NPG Asia Mater., Analytical Chemistry, Biosensors Bioelectronics等发表SCI论文60余篇,申请专利3项;参编Springer著作《Nucleic acid amplification strategies for biosensing, bioimaging and biomedicine》,撰写章节两节,参编科学出版社著作《功能化纳米材料在生化分析中的应用》,撰写章节一节。相关研究成果已被 Chem. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed.等国际知名刊物引用近2000次。现兼任中国青年科技工作者协会会员,SCI杂志Technology in Cancer Research & Treatment 、Frontiers in Chemistry副主编(Associate Editor),Nano Materials Science、VIEW、分析试验室 青年编委。
代表性论著:
(1)L. L. Zheng, J. Z. Li, M. Wen, D. Xi, Y. Zhu, Q. Wei, X.-B. Zhang, G. Ke*, F. Xia*, Z. F. Gao*, Enthalpy and entropy synergistic regulation-based programmable DNA motifs for biosensing and information encryption. Science Advances, 2023, 9, eadf5868. (Science 子刊)
(2)Z. F. Gao, R. Liu, J. Wang, J. Dai, W. H. Huang, M. Liu, S. Wang, F. Xia*, S. Zhang*, L. Jiang, Manipulating the hydrophobicity of DNA as a universal strategy for visual biosensing. Nature Protocols 2020, 15, 316– 337. (Nature 子刊)
(3) Z. F. Gao, R. Liu, J. Wang, J. Dai, W. H. Huang, M. Liu, S. Wang, F. Xia*, L. Jiang, Controlling droplet motion on an organogel surface by tuning the chain length of DNA and its biosensing application. Chem 2018, 4, 2929-2943. (Cell姊妹刊)
(4) X. Yang#, J. Wang#, Z. F. Gao#, W. Zhang, H. Zhu, Y. Song, Q. Wang, M. Liu, L. Jiang, Y. Huang*, F. Xia*, An orthogonal dual-regulation strategy for sensitive biosensing applications. National Science Review 2022, 9, nwac048.
(5)Z. F. Gao, H. Zhu, Y. Li, X. Yang, X. Ren, D. Wu, H. Ma, Q. Wei*, F. Xia*, H. Ju*, Revolutionizing biosensing with superwettability: Designs, mechanisms, and applications. Nano Today 2023, 53, 102008.
(6)Y. L. Li, X. H. Min, Y. J. Fan, J. X. Dong, D. Wu, X. Ren, H. M. Ma, Z. F. Gao*, Q. Wei, F. Xia, H. Ju. Photocleavable DNA Nanotube-Based Dual-Amplified Resonance Rayleigh Scattering System for MicroRNA Detection Incorporating Molecular Computing-Cascaded Keypad Lock Functionality, Analytical Chemistry 2024, 96, 2983-2989.
(7)H. Wang, Y. L. Li, Y. J. Fan, J. X. Dong, X. Ren, H. Ma, D. Wu, Z. F. Gao*, Q. Wei., F. Xia, DNA Tile and Invading Stacking Primer-Assisted CRISPR−Cas12a Multiple Amplification System for Entropy-Driven Electrochemical Detection of MicroRNA with Tunable Sensitivity. Analytical Chemistry 2023, 95, 13659−13667.
(8)J. X. Dong, S. M. Zhang, Y. L. Li, X. Zhang, Y. J. Fan, M. Su, Z. G. Wang, H. Li, S. G.Shen, Z. F. Gao*, Q. Wei., F. Xia, Photocontrollable DNA Walker-Based Molecular Circuit for the Tunable Detection of MicroRNA-21 Using Metal−Organic Frameworks as Label-Free Fluorescence Tags. Analytical Chemistry 2023, 95, 16744−16753
(9) Y. J. Fan, J. X. Dong,* Y. L. Li, Z. G. Wang, Y. Q. Chang, L. F. Ren, M. Su, L. Guan, S. G. Shen,* Z. F. Gao*, Q. Wei., F. Xia, D‑Penicillamine@Ag/Cu Nanocluster-Based Fluorescent Nanoneuron for Logic Screening Phosphonate-Type Organophosphate Pesticides and Steganographically Encrypting Information. Analytical Chemistry 2023, 95, 11113−11123.
(10) Z. F. Gao*, L. L. Zheng, L. M. Dong, J. Z. Li, Y. Shen*, P. Chen*, F. Xia, Label-Free Resonance Rayleigh Scattering Amplification for Lipopolysaccharide Detection and Logical Circuit by CRISPR/Cas12a-Driven Guanine Nanowire Assisted Non-Crosslinking Hybridization Chain Reaction. Analytical Chemistry 2022, 94, 6371−6379.
(11)J. J. Zhang, C. Nie, W. L. Fu, F. L. Cheng, P. Chen, Z. F. Gao*, Y. Wu, Y. Shen*, Photoresponsive DNA-Modified Magnetic Bead-Assisted Rolling Circle Amplification-Driven Visual Photothermal Sensing of Escherichia coli. Analytical Chemistry 2022, 94, 16796−16802.
An updated list of publications can be found on: https://www.webofscience.com/wos/author/record/N-4792-2014