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  • 其他栏目

    葛慎光

    • 教授 博士生导师 硕士生导师
    • 性别:男
    • 出生日期:1980-01-05
    • 毕业院校:山东大学
    • 学历:博士研究生毕业
    • 学位:理学博士学位
    • 在职信息:在职
    • 所在单位:前沿交叉科学研究院
    • 入职时间: 2006-07-01
    • 学科:化学
    • 办公地点:化学楼B204
    • 联系方式:电话:13589047392 e-mail:chm_gesg@ujn.edu.cn

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    个人简介:

    葛慎光,教授,硕士生/博士生导师,主要从事功能纳米材料制备、生物传感器信号转换与放大新原理和新方法、生物传感器的构建及应用、纸芯片器件的开发和研制、微流控纸芯片性能调控和传感机制研究等。以第一作者或通讯作者在 Anal. Chem.NanoscaleACS Appl. Mater. Interfaces 等期刊共发表 SCI收录论文100余篇;第一发明人获授权发明专利16项。主持国家自然科学基金项目4项,山东省优青项目1项,山东省重点研发计划2项等项目10余项;以第二完成人获得2016年度山东省自然科学一等奖,2015年度中国石油和化学工业联合会科技进步二等奖;第一完成人获得2017年度中国分析测试协会科学技术二等奖。指导学生获得挑战杯全国大学生课外学术科技作品竞赛一等奖等国家级及省级科创奖励多项。

     

    主讲课程:分析化学、新型功能材料、生物分析

    科研方向:

    1. 纳米材料制备及生物应用

    2. 生物传感器的构建及临床分子诊断

    3. 微流控纸芯片生物传感器件研制

    主持部分项目:

    1.国家自然科学基金面上项目-可编程DNA步行者双极电极纸芯片构建及循环肿瘤DNA检测-(22074053)

    2. 国家自然科学基金面上项目-纸芯片甄别检测高侵袭恶性循环肿瘤细胞的新方法-(21775055

    3. 国家自然科学基金面上项目-基于中空通道纸芯片的自推进分离捕获循环肿瘤细胞及原位分析-(No.21575051)

    4. 国家自然科学基金青年基金-基于点击化学的微囊藻毒素化学传感器构建-No.21207048)

    5. 山东省优青项目-多功能纸芯片分离捕获外周血中肿瘤细胞及原位分析-No.ZR2015JL006

    6. 山东省高等学校青创科技支持计划-纸芯片即时检测方法与应用-2019KJC016

    7. 山东省重点研发计划-原发性肝癌快速检测辅助诊断纸芯片试剂盒研制-2018GGX103037

    8. 山东省科技发展计划-研制纸芯片器件对水体中农药残留的检测与监控-No. 2014GGX103012

    9. 济南市青年科技明星计划-含反应基团的Si/C/N陶瓷前驱体聚硅氮烷的制备及性能研究-No.20110102

    10. 中国科学院环境化学与生态毒理学国家重点实验室开放基金-基于纸微芯片的电化学发光免疫分析研究-No.KF2011-03

     

    科技获奖

    1.基于结构调控和光电性能的纸芯片微流控基础研究与传感机制,山东省自然科学一等奖。

    2.纸芯片生物传感分析新方法及应用,中国分析测试协会科学技术二等奖。

    3.纸芯片传感器纳米材料构建传感界面和实现信号放大,山东省高等学校优秀科研成果一等奖。

    4.微流控纸芯片的功能调控技术及其应用,中国石油与化学工业联合会二等奖。

    5.含共轭结构的有机硅聚合物的制备及应用,山东省科技进步三等奖。

     

    代表性论文:

    1. Jinge Zhao, Cuiping Fu, Chuan Huang, Sibao Zhang, Fangfang Wang, Yan Zhang*, Lina Zhang, Shenguang Ge*, Jinghua Yu, Co3O4-Au Polyhedron Mimic Peroxidase- and Cascade Enzyme-assisted Cycling Process-Based Photoelectrochemical Biosensor for Monitoring of miRNA-141, Chemical Engineering Journal, 2021, 406, 126892.

    2.Yanhu Wang, Huihui Shi, Lina Zhang, Shenguang Ge*, Meiling Xu, Xiao Wang *, Jinghua Yu, Two-dimensional black phosphorus nanoflakes: a coreactant-free electrochemiluminescence luminophors for selective Pb2+ detection based on resonance energy transfer, Journal of Hazardous Materials, 2021, 403, 123601.

    3. Yanhu Wang, Huihui Shi, Kang Cui, Lina Zhang, Shenguang Ge*, Jinghua Yu, Reversible Electron Storage in Tandem Photoelectrochemical Cell for Light Driven Unassisted Overall Water Splitting, Applied Catalysis B: Environmental, 2020, 275: 119094

    4. Shaopeng Wang, Fangfang Wang, Cuiping Fu, Yina Sun, Jinge Zhao, Na Li, Yunqing Liu*, Shenguang Ge*, Jinghua Yu, AgInSe2-Sensitized ZnO Nanoflowers Wide Spectrum Response Photoelectrochemical/Visual Sensing Platform via Au@Nanorods-Anchored CeO2 Octahedron Regulated Signal, Analytical Chemistry, 2020, 92, 76047611.

    5. Chaomin Gao, Haihan Yu, Yanhu Wang, Dezhong Liu, Ting Wen, Lina Zhang,* Shenguang Ge,* and Jinghua Yu, Paper-Based Constant Potential Electrochemiluminescence Sensing Platform with Black Phosphorus as a Luminophore Enabled by Perovskite Solar Cell, Analytical Chemistry, 2020, 92, 10, 6822-6826.

    6. Peini Zhao, Huanying Liu, Lina Zhang, Peihua Zhu, Shenguang Ge,* and Jinghua Yu, Paper-Based SERS Sensing Platform Based on 3D Silver Dendrites and Molecularly Imprinted Identifier Sandwich Hybrid for Neonicotinoid Quantification, ACS Applied Materials & Interfaces, 2020, 12, 7, 8845-8854

    7. Chaomin Gao, Jie Xue, Lina Zhang, Peini Zhao, Kang Cui, Shenguang Ge*, Jinghua Yu, Paper based modification-free photoelectrochemical sensing platform with single-crystalline aloe like TiO2 as electron transporting material for cTnI detection, Biosensors and Bioelectronics, 2019, 131, 17-23.

    8. Xiaolu Sun, Yannan Jian, He Wang, Shenguang Ge*, Mei Yan, Jinghua Yu, Ultrasensitive microfluidic paper-based electrochemical biosensor based on molecularly imprinted film and boronate affinity sandwich assay for glycoprotein detection, ACS Applied Materials & Interfaces, 2019, 11 (17), 16198–16206.

    9. Shaopeng Wang, Jinge Zhao, Yan Zhang, Mei Yan, Lina Zhang, Shenguang Ge*, Jinghua Yu, Photoelectrochemical Biosensor of HIV-1 Based on Cascaded Photoactive Materials and Triple-Helix Molecular Switch, Biosensors and Bioelectronics, 2019, 139, 111325.

    10. Shenguang Ge,* Jinge Zhao, Shaopeng Wang, Feifei Lan, Mei Yan, Jinghua Yu, Ultrasensitive electrochemiluminescence assay of tumor cells and evaluation of H2O2 on a paper-based closed-bipolar electrode by in-situ hybridization chain reaction amplification, Biosensors and Bioelectronics, 2018, 102, 411-417.

    11. Xiaoxiao Zheng, Li Li, Kang Cui, Yan Zhang, Lina Zhang, Shenguang Ge*, Jinghua Yu, Ultrasensitive Enzyme-free Biosensor by Coupling Cyclodextrin Functionalized Au Nanoparticles and High Performance Au-Paper ElectrodeACS Applied Materials & Interfaces, 2018, 10, 33333340.

    12. Xiaolu Sun, He Wang, Yannan Jian, Feifei Lan, Lina Zhang, Haiyun Liu*, Shenguang Ge*, Jinghua Yu, Ultrasensitive microfluidic paper-based electrochemical/visual biosensor based on spherical-like cerium dioxide catalyst for miR-21 detection, Biosensors and Bioelectronics, 2018, 105, 218-225.

    13. Hongmei Yang, Yan Zhang, Lina Zhang, Kang Cui, Shenguang Ge*, Jiadong Huang, and Jinghua Yu, Stackable Lab-on-Paper Device with All-in-One Au Electrode for High-Efficiency Photoelectrochemical Cyto-Sensing, Analytical Chemistry, 2018, 90, 7212–7220.

    14. He Wang, Chenxi Zhou, Xiaolu Sun, Yannan Jian, Qingkun Kong, Kang Cui, Shenguang Ge*, Jinghua Yu, Polyhedral-AuPd Nanoparticles-Based Dual-Mode Cytosensor with Turn on Enable Signal for Highly Sensitive Cell Evalution on Lab-on-Paper Device, Biosensors and Bioelectronics, 2018, 117, 651-658.

    15. Yanhu Wang , Lina Zhang , Qingkun Kong, Shenguang Ge*, Jinghua Yu, Time-resolution addressable photoelectrochemical strategy based on hollow-channel paper analytical devices, Biosensors and Bioelectronics, 2018, 120, 64-70.

    16. Shenguang Ge,† Lina Zhang,† Yan Zhang, Feifei Lan, Mei Yan, Jinghua Yu*, Nanomaterials Modified Cellulose Paper as a Platform for Biosensing Application, Nanoscale, 2017, 9, 4366-4382

    17. Shenguang Ge†, Feifei Lan†, Linlin Liang, Na Ren, Li Li, Haiyun Liu, Mei Yan, Jinghua Yu*, Ultrasensitive Photoelectrochemical Biosensing of Cell Surface N-glycan Expression Based on the Enhancement of Nanogold-assembled Mesoporous Silica Amplified by Graphene Quantum Dots and hybridization Chain Reaction, ACS Applied Materials & Interfaces, 2017, 9(8), 6670-6678.

    18. Linlin Liang, Feifei Lan, Shenguang Ge,* Jinghua Yu, Na Ren, and Mei Yan, Metal-Enhanced Ratiometric Fluorescence/Naked Eye Bimodal Biosensor for Lead Ions Analysis with Bifunctional Nanocomposite Probes, Analytical Chemistry, 2017, 89, 3597-3605.

    19. Linlin Liang, Feifei Lan, Xuemei Yin, Shenguang Ge*, Jinghua Yu, Mei Yan, Metal-Enhanced Fluorescence/Visual Bimodal Platform forMultiplexed Ultrasensitive Detection of MicroRNA with Reusable Paper Analytical Devices, Biosensors and Bioelectronics, 2017, 95, 181-188.

    20. Yuzhen Huang, Li Li, Yan Zhang, Lina Zhang, Shenguang Ge*, Hao Li, Jinghua Yu, Cerium Dioxide Mediated Signal ‘on-off’ by Resonance Energy Transfer on Lab-on-paper Device for Ultrasensitive Detection of Lead Ion, ACS Applied Materials & Interfaces, 2017, 9 (38), 32591-32598.

     

     

    代表性授权发明专利:

    1. 一种基于功能化金属有机框架材料的电致化学发光传感器-(发明专利:ZL 2017107568616

    2. 检测癌细胞表面多糖表达的光致电化学纸芯片的制备-(发明专利:ZL2016105844890

    3. 癌细胞及细胞表面多糖检测荧光-比色双模式纸芯片的制备-(发明专利:ZL2016103848365

    4. 一种金属有机框架材料表面负载分子印迹聚合物膜用于乙酰甲胺磷的电化学检测方法-(发明专利:ZL2016106840064

    5. 一种化学发光光致电化学传感器的制备及有机磷类农药检测-(发明专利:ZL2016106840007

    6. 一种基于便携式血糖仪检测凝血酶的纸分析器件的构建-(发明专利:ZL2016109423424

    7. 点击化学技术制备分子印迹纸芯片传感器-(发明专利:ZL201510480233.0

    8. 一种电聚合分子印迹聚合物中空通道纸器件的制备及在农药残留即时检测中的应用-(发明专利:ZL201410436014.8

    9.用于叶酸过表达癌细胞快速检测的比色方法-(发明专利:ZL201410124906.4)

    10.一种基于点击化学仿生分子印迹电化学传感器的制备及对食品过敏原的检测-(发明专利:ZL201210472177.2

     

    学生科创:

    1. 第十五届挑战杯”·中国银行全国大学生课外学术科技作品竞赛一等奖,指导教师:葛慎光,2017.11

    2. 第十五届挑战杯”·海尔山东省大学生课外学术科技作品竞赛决赛特等奖,指导教师:葛慎光,2017.5

    3. 首届山东省大学生科技创新大赛二等奖,指导教师:葛慎光,2014-12-15.

    4. 第三届山东省大学生科技创新大赛二等奖,指导教师:葛慎光,2016-12.

    5. 国家级大学生创新创业训练计划,指导教师:葛慎光

     

    其他联系方式

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    教育经历

    2010.9 -- 2013.12
    山东大学       化学

    2003.9 -- 2006.7
    济南大学       应用化学

    1999.9 -- 2003.7
    济南大学       应用化学

    工作经历

    2017.12 -- 至今

    济南大学      教授

    2014.1 -- 2017.11

    济南大学      副教授

    2008.11 -- 2013.12

    济南大学      讲师

    研究方向

  • 1. 纳米材料制备及生物应用
    2. 生物传感器的构建及临床分子诊断
    3. 微流控纸芯片生物传感器件研制